ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases
C. Leah B. Kline1,2,*, A. Pieter J. Van den Heuvel1,*,†, Joshua E. Allen1,3, Varun V. Prabhu1,2, David T. Dicker1,2, and Wafik S. El-Deiry1,2,‡
Sci. Signal. 16 Feb 2016:
Vol. 9, Issue 415, pp. ra18
- DOI:
http://dx.doi.org/10.1126/scisignal.aac4374
