1.
Applications of a Blood-Brain Barrier Technology Platform to Predict CNS Penetration of Various Chemotherapeutic Agents. 1. Anti-Infective Drugs
M. Adenota, N. Perrierea, b, J.M. Scherrmannb, R. Lahanaa
Chemotherapy 2007;53:70-72 (DOI: 10.1159/000098421)
- DOI:
http://dx.doi.org/http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000098421#OLN[/code]
Predicting Penetration Across the Blood-Brain Barrier from Simple Descriptors and Fragmentation Schemes
Yuan H. Zhao,† Michael H. Abraham,*† Adam Ibrahim,† Paul V. Fish,‡ Susan Cole, Mark L. Lewis, Marcel J. de Groot,# and Derek P. Reynolds§
Department of Chemistry, University College London, London WC1H 0AJ, U.K., Departments of Discovery Chemistry, Pharmacokinetics & Drug Metabolism, and Computational Chemistry, Pfizer Global Research and Development, Ramsgate Road, Sandwich, Kent CT13 9NJ, U.K., and REYTEK, 11C Rothsay Road, Bedford MK40 3PP, U.K.
J. Chem. Inf. Model., 2007, 47 (1), pp 170–175
DOI: 10.1021/ci600312d
- DOI:
http://dx.doi.org/http://pubs.acs.org/doi/abs/10.1021/ci600312d