Protease Inhibitors: Synthesis and QSAR Study of Novel Classes of Nonbasic Thrombin Inhibitors Incorporating Sulfonylguanidine and O-Methylsulfonylisourea Moieties at P1
Claudiu T. Supuran,*† Andrea Scozzafava,† Fabrizio Briganti,† and Brian W. Clare*‡
J. Med. Chem., 2000, 43 (9), pp 1793–1806
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http://dx.doi.org/10.1021/jm9903693