1)
Incorporation of Basic Side Chains into Cryptolepine Scaffold: Structure−Antimalarial Activity Relationships and Mechanistic Studies
Joao Lavrado, Ghislain G. Cabal, Miguel Prudencio, Maria M. Mota, Jiri Gut, Philip J. Rosenthal, Cecilia Diaz, Rita C. Guedes, Daniel J. V. A. dos Santos, Elena Bichenkova, Kenneth T. Douglas, Rui Moreira, and Alexandra Paulo
J. Med. Chem., 2011, 54 (3), pp 734–750
- DOI:
http://dx.doi.org/10.1021/jm101383f
Synthesis and Biological Evaluation of Analogues of Cryptolepine, an Alkaloid Isolated from the Suriname Rainforest1
Shu-Wei Yang, Maged Abdel-Kader, Stan Malone, Marga C. M. Werkhoven, Jan H. Wisse, Isia Bursuker, Kim Neddermann, Craig Fairchild, Carmen Raventos-Suarez, Ana T. Menendez, Kate Lane, and David G. I. Kingston
J. Nat. Prod., 1999, 62 (7), pp 976–983
- DOI:
http://dx.doi.org/10.1021/np990035g
Synthesis of Some Cryptolepine Analogues, Assessment of Their Antimalarial and Cytotoxic Activities, and Consideration of Their Antimalarial Mode of Action
Onyeka Onyeibor, Simon L. Croft, Hilary I. Dodson, Mohammad Feiz-Haddad, Howard Kendrick, Nicola J. Millington, Silvia Parapini, Roger M. Phillips, Scott Seville, Steven D. Shnyder, Donatella Taramelli, and Colin W. Wright
J. Med. Chem., 2005, 48 (7), pp 2701–2709
- DOI:
http://dx.doi.org/10.1021/jm040893w
Synthesis and Evaluation of Cryptolepine Analogues for Their Potential as New Antimalarial Agents
Colin W. Wright, Jonathan Addae-Kyereme, Anthony G. Breen, John E. Brown, Marlene F. Cox, Simon L. Croft, Yaman Gökçek, Howard Kendrick, Roger M. Phillips, and Pamela L. Pollet
J. Med. Chem., 2001, 44 (19), pp 3187–3194
- DOI:
http://dx.doi.org/10.1021/jm010929+
Synthesis, Cytotoxicity, and Antiplasmodial and Antitrypanosomal Activity of New Neocryptolepine Derivatives
Tim H. M. Jonckers, Sabine van Miert, Kanyanga Cimanga, Christian Bailly, Pierre Colson, Marie-Claire De Pauw-Gillet, Hilde van den Heuvel, Magda Claeys, Filip Lemière, Eddy L. Esmans, Jef Rozenski, Ludo Quirijnen, Louis Maes, Roger Dommisse, Guy L. F. Lemière, Arnold Vlietinck, and Luc Pieters
J. Med. Chem., 2002, 45 (16), pp 3497–3508
- DOI:
http://dx.doi.org/10.1021/jm011102i
An Expeditious I2-Catalyzed Entry into 6H-Indolo[2,3-b]quinoline System of Cryptotackieine
Prakash T. Parvatkar, Perunninakulath S. Parameswaran and Santosh G. Tilve
J. Org. Chem., 2009, 74 (21), pp 8369–8372
- DOI:
http://dx.doi.org/10.1021/jo901361x
Ibrahim El Sayed, Pieter Van der Veken, Koen Steert, Liene Dhooghe, Steven Hostyn, Gitte Van Baelen, Guy Lemiere, Bert U. W. Maes, Paul Cos, Louis Maes, Jurgen Joossens, Achiel Haemers, Luc Pieters and Koen Augustyns
J. Med. Chem., 2009, 52 (9), pp 2979–2988
- DOI:
http://dx.doi.org/10.1021/jm801490z
Efficient Syntheses of the Unknown Quinolino[2,3-c]cinnolines; Synthesis of Neocryptolepines
Makhluf J. Haddadin, Raghida M. Bou Zerdan, Mark J. Kurth, and James C. Fettinger
Org. Lett., 2010, 12 (23), pp 5502–5505
- DOI:
http://dx.doi.org/10.1021/ol102376a