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From a Natural Product Lead to the Identification of Potent and Selective Benzofuran-3-yl-(indol-3-yl)maleimides as Glycogen Synthase Kinase 3β Inhibitors That Suppress Proliferation and Survival of Pancreatic Cancer Cells
Irina N. Gaisina†, Franck Gallier†, Andrei V. Ougolkov‡, Ki H. Kim†, Toru Kurome†, Songpo Guo†, Denise Holzle§, Doris N. Luchini‡, Sylvie Y. Blond§, Daniel D. Billadeau*‡ and Alan P. Kozikowski*
J. Med. Chem., 2009, 52 (7), pp 1853–1863
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http://dx.doi.org/10.1021/jm801317horganic