shura_zd писал(а):1. Pech, R.; Mertens, Jutta; Boehm, R.; Pharmazie; vol. 46; nb. 6; (1991); p. 422 - 423
THIENO COMPOUNDS .11. SYNTHESIS OF 4-AMINO-SUBSTITUTED THIENO[2,3-D]PYRIMIDIN-2-YLCARBOXYLIC ACID-DERIVATIVES
Author(s): PECH R, MERTENS J, BOHM R
Source: PHARMAZIE Volume: 46 Issue: 6 Pages: 422-423 Published: JUN 1991
Times Cited: 0 References: 12 Citation MapCitation Map
Abstract: Starting from esters of 3,4-dihydro-4-oxothieno[2,3-d]pyrimidin-2-ylcarboxylic acids the 4-chloro derivatives were prepared. By reaction with aliphatic and aromatic amines the corresponding esters of 4-alkylamino- and 4-arylamino-thieno[2,3-d]pyrimidin-2-ylcarboxylic acids were obtained. Only in few cases the ester group reacts to give the carboxylic amids.
Document Type: Article
Language: German
KeyWords Plus: DERIVATIVES
Reprint Address: PECH, R (reprint author), MARTIN LUTHER UNIV HALLE WITTENBERG, FACHBEREICH PHARM, WEINBERGWEG 15, O-4050 HALLE, GERMANY
Publisher: GOVI-VERLAG GMBH, PHARMAZEUTISCHER VERLAG GINNHEIMER STRASSE 26, D-65760 ESCHBORN, GERMANY
IDS Number: FX917
ISSN: 0031-7144