J. Med. Chem., 2000, 43 (6), pp 1187–1202
Design and SAR of Novel Potassium Channel Openers Targeted for Urge Urinary Incontinence. 1. N-Cyanoguanidine Bioisosteres Possessing in Vivo Bladder Selectivity
John A. Butera,*† Madelene M. Antane,† Schuyler A. Antane,† Thomas M. Argentieri,‡ Chris Freeden,# Russell F. Graceffa,† Bradford H. Hirth,† Douglas Jenkins,† Joseph R. Lennox,† Edward Matelan,† N. Wesley Norton,‡ Dominick Quagliato,† Jeffrey H. Sheldon,‡ Walter Spinelli,# Dawn Warga,‡ Alexandra Wojdan,# and Morgan Woods‡
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http://dx.doi.org/10.1021/jm9905099
